APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly

Advanced age and apolipoprotein E (APOE) ε4 allele are both associated with increased risk of the Alzheimer’s disease (AD). However, the extent of the joint contribution of APOE ε4 allele and age on the brain white matter integrity, cognition and their relationship are unclear. We assessed the age-r...

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Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Sun, Jinping, Zhu, Zhibao, Chen, Kewei, Wei, Dongfeng, Li, Xin, Li, He, Zhang, Junying, Chen, Xiaochun, Chen, Yaojing, Zhang, Zhanjun
Format: Artigo
Langue:Inglês
Publié: Impact Journals 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343443/
https://ncbi.nlm.nih.gov/pubmed/32572010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103367
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