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SARS-CoV-2 strategically mimics proteolytic activation of human ENaC
Molecular mimicry is an evolutionary strategy adopted by viruses to exploit the host cellular machinery. We report that SARS-CoV-2 has evolved a unique S1/S2 cleavage site, absent in any previous coronavirus sequenced, resulting in the striking mimicry of an identical FURIN-cleavable peptide on the...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7343387/ https://ncbi.nlm.nih.gov/pubmed/32452762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58603 |
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