Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane

HIV-1 assembly occurs principally at the plasma membrane (PM) of infected cells. Gag polyprotein precursors (Pr55(Gag)) are targeted to the PM, and their binding is mediated by the interaction of myristoylated matrix domain and a PM-specific phosphoinositide, the phosphatidylinositol-(4,5)-bisphosph...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Gonzales, Baptiste, de Rocquigny, Hugues, Beziau, Anne, Durand, Stephanie, Burlaud-Gaillard, Julien, Lefebvre, Antoine, Krull, Sandra, Emond, Patrick, Brand, Denys, Piver, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343192/
https://ncbi.nlm.nih.gov/pubmed/32376619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00189-20
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