Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane

HIV-1 assembly occurs principally at the plasma membrane (PM) of infected cells. Gag polyprotein precursors (Pr55(Gag)) are targeted to the PM, and their binding is mediated by the interaction of myristoylated matrix domain and a PM-specific phosphoinositide, the phosphatidylinositol-(4,5)-bisphosph...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Gonzales, Baptiste, de Rocquigny, Hugues, Beziau, Anne, Durand, Stephanie, Burlaud-Gaillard, Julien, Lefebvre, Antoine, Krull, Sandra, Emond, Patrick, Brand, Denys, Piver, Eric
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343192/
https://ncbi.nlm.nih.gov/pubmed/32376619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00189-20
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