Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane

HIV-1 assembly occurs principally at the plasma membrane (PM) of infected cells. Gag polyprotein precursors (Pr55(Gag)) are targeted to the PM, and their binding is mediated by the interaction of myristoylated matrix domain and a PM-specific phosphoinositide, the phosphatidylinositol-(4,5)-bisphosph...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Gonzales, Baptiste, de Rocquigny, Hugues, Beziau, Anne, Durand, Stephanie, Burlaud-Gaillard, Julien, Lefebvre, Antoine, Krull, Sandra, Emond, Patrick, Brand, Denys, Piver, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343192/
https://ncbi.nlm.nih.gov/pubmed/32376619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00189-20
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