Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55(Gag) to the Plasma Membrane

HIV-1 assembly occurs principally at the plasma membrane (PM) of infected cells. Gag polyprotein precursors (Pr55(Gag)) are targeted to the PM, and their binding is mediated by the interaction of myristoylated matrix domain and a PM-specific phosphoinositide, the phosphatidylinositol-(4,5)-bisphosph...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gonzales, Baptiste, de Rocquigny, Hugues, Beziau, Anne, Durand, Stephanie, Burlaud-Gaillard, Julien, Lefebvre, Antoine, Krull, Sandra, Emond, Patrick, Brand, Denys, Piver, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343192/
https://ncbi.nlm.nih.gov/pubmed/32376619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00189-20
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