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Progressive familial intrahepatic cholestasis type 4 in an Indian child: presentation, initial course and novel compound heterozygous mutation

A 15-year-old boy who had a history of on and off pruritus and jaundice since many years found to have a novel mutation in TJP2 gene. On examination, he had clubbing, splenomegaly, grade 3 oesophageal varices and short stature. Investigation revealed direct hyperbirubinemia with elevated liver enzym...

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Détails bibliographiques
Publié dans:BMJ Case Rep
Auteurs principaux: Mirza, Nida, Bharadwaj, Ravi, Malhotra, Smita, Sibal, Anupam
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342223/
https://ncbi.nlm.nih.gov/pubmed/32636225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2019-234193
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