Inhaled nebulized nitrite and nitrate therapy in a canine model of hypoxia-induced pulmonary hypertension

Dysfunction in the nitric oxide (NO) signaling pathway can lead to the development of pulmonary hypertension (PH) in mammals. Discovery of an alternative pathway to NO generation involving reduction from nitrate to nitrite and to NO has motivated the evaluation of nitrite as an alternative to inhale...

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Detalhes bibliográficos
Publicado no:Nitric Oxide
Main Authors: Cortés-Puch, Irene, Sun, Junfeng, Schechter, Alan N., Solomon, Steven B., Park, Ji Won, Feng, Jing, Gilliard, Cameron, Natanson, Charles, Piknova, Barbora
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341979/
https://ncbi.nlm.nih.gov/pubmed/31299340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2019.07.001
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