Inhaled nebulized nitrite and nitrate therapy in a canine model of hypoxia-induced pulmonary hypertension

Dysfunction in the nitric oxide (NO) signaling pathway can lead to the development of pulmonary hypertension (PH) in mammals. Discovery of an alternative pathway to NO generation involving reduction from nitrate to nitrite and to NO has motivated the evaluation of nitrite as an alternative to inhale...

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Veröffentlicht in:Nitric Oxide
Hauptverfasser: Cortés-Puch, Irene, Sun, Junfeng, Schechter, Alan N., Solomon, Steven B., Park, Ji Won, Feng, Jing, Gilliard, Cameron, Natanson, Charles, Piknova, Barbora
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341979/
https://ncbi.nlm.nih.gov/pubmed/31299340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2019.07.001
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