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Down-Regulation of the Mammalian Target of Rapamycin (mTOR) Pathway Mediates the Effects of the Paeonol-Platinum(II) Complex in Human Thyroid Carcinoma Cells and Mouse SW1736 Tumor Xenografts

BACKGROUND: This study aimed to investigate the effects of the paeonol-platinum(II) (PL-Pt[II]) complex on SW1736 human anaplastic thyroid carcinoma cell line and the BHP7-13 human thyroid papillary carcinoma cell line in vitro and on mouse SW1736 tumor xenografts in vivo. MATERIAL/METHODS: The cyto...

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Vydáno v:Med Sci Monit
Hlavní autoři: He, Ling, Guo, Song, Zhu, Taiyang, Chen, Chen, Xu, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341900/
https://ncbi.nlm.nih.gov/pubmed/32594094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.922561
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