Renal cancer-derived exosomes induce tumor immune tolerance by MDSCs-mediated antigen-specific immunosuppression

BACKGOUND: Although Myeloid-derived suppressor cells (MDSCs) have a prominent ability to suppress the immune responses of T lymphocytes and propel tumor immune escape, a lack of profound systemic immunesuppression in tumor-bearing mice and tumor patients. The underlying mechanism of these remains un...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Gao, Yingying, Xu, Haoyu, Li, Nan, Wang, Hexi, Ma, Lei, Chen, Shiyou, Liu, Jiayu, Zheng, Yongbo, Zhang, Yao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341585/
https://ncbi.nlm.nih.gov/pubmed/32641056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00611-z
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