A Systematic Review Comparing Experimental Design of Animal and Human Methotrexate Efficacy Studies for Rheumatoid Arthritis: Lessons for the Translational Value of Animal Studies

SIMPLE SUMMARY: If we want to use animal studies to predict what will happen if we give a drug to humans, it makes sense to perform the animal studies as similarly to human studies as possible. For example, if animal tests of a drug only look at the effect of injecting the drug in young healthy anim...

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Detalhes bibliográficos
Publicado no:Animals (Basel)
Main Authors: Leenaars, Cathalijn, Stafleu, Frans, de Jong, David, van Berlo, Maikel, Geurts, Tijmen, Coenen-de Roo, Tineke, Prins, Jan-Bas, Kempkes, Rosalie, Elzinga, Janneke, Bleich, André, de Vries, Rob, Meijboom, Franck, Ritskes-Hoitinga, Merel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341304/
https://ncbi.nlm.nih.gov/pubmed/32560528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10061047
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