A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice

Several virtual screening models are proposed to screen small molecules only targeting primary miRNAs without selectivity. Few attempts have been made to develop virtual screening strategies for discovering small molecules targeting mature miRNAs. Mature miRNAs and their specific target mRNA can for...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Zhuo, Zhenjian, Wan, Youyang, Guan, Daogang, Ni, Shuaijian, Wang, Luyao, Zhang, Zongkang, Liu, Jin, Liang, Chao, Yu, Yuanyuan, Lu, Aiping, Zhang, Ge, Zhang, Bao‐Ting
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341099/
https://ncbi.nlm.nih.gov/pubmed/32670749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201903451
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados