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Clinical promise of next-generation complement therapeutics
The complement system plays a key role in pathogen immunosurveillance and tissue homeostasis. However, subversion of its tight regulatory control can fuel a vicious cycle of inflammatory damage that exacerbates pathology. The clinical merit of targeting the complement system has been established for...
Enregistré dans:
| Publié dans: | Nat Rev Drug Discov |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7340853/ https://ncbi.nlm.nih.gov/pubmed/31324874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0031-6 |
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