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Synthesis and dopamine receptor pharmacological evaluations on ring C ortho halogenated 1-phenyl-benzazepines
A series of 1-phenyl-benzazepines containing bromine or chlorine substituents at the ortho position of the appended phenyl ring (2’-monosubstituted or 2’,6’- disubstituted patterns) were synthesized and evaluated for affinity towards dopamine D(1)R, D(2)R and D(5)R. As is typical of the 1-phenyl-ben...
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| Veröffentlicht in: | Bioorg Med Chem Lett |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7340849/ https://ncbi.nlm.nih.gov/pubmed/32631525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127305 |
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