SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration

SOCS3, a feedback inhibitor of the JAK/STAT signal pathway, negatively regulates axonal regrowth and inflammation in the central nervous system (CNS). Here, we demonstrated a distinct role of SOCS3 in the injured spinal cord of the gecko following tail amputation. Severing the gecko spinal cord did...

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Bibliografiske detaljer
Udgivet i:Neurosci Bull
Main Authors: Zhang, Xuejie, He, Bingqiang, Li, Hui, Wang, Yingjie, Zhou, Yue, Wang, Wenjuan, Song, Tiancheng, Du, Nan, Gu, Xingxing, Luo, Yi, Wang, Yongjun
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340708/
https://ncbi.nlm.nih.gov/pubmed/32306216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00493-8
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