IL-34 Induces the Differentiation of Human Monocytes into Immunosuppressive Macrophages. Antagonistic Effects of GM-CSF and IFNγ

IL-34 is a recently identified cytokine that signals via the M-CSF receptor and promotes monocyte survival. Depending on the environment, monocytes can differentiate into macrophages (Mφ) or dendritic cells (DC). A wide spectrum of Mφ and DC subsets, with distinct phenotypes and functions, has been...

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Détails bibliographiques
Auteurs principaux: Foucher, Etienne D., Blanchard, Simon, Preisser, Laurence, Garo, Erwan, Ifrah, Norbert, Guardiola, Philippe, Delneste, Yves, Jeannin, Pascale
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568045/
https://ncbi.nlm.nih.gov/pubmed/23409120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056045
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