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Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase

Coproporphyrin ferrochelatases (CpfCs, EC 4.99.1.9) insert ferrous iron into coproporphyrin III yielding coproheme. CpfCs are utilized by prokaryotic, mainly monoderm (Gram-positive) bacteria within the recently detected coproporphyrin-dependent (CPD) heme biosynthesis pathway. Here, we present a co...

詳細記述

保存先:
書誌詳細
出版年:FEBS J
主要な著者: Hofbauer, Stefan, Helm, Johannes, Obinger, Christian, Djinović-Carugo, Kristina, Furtmüller, Paul G.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340540/
https://ncbi.nlm.nih.gov/pubmed/31794133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15164
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