Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction

Parkinson’s disease (PD) is a neurodegenerative disorder featuring progressive loss of midbrain dopaminergic (DA) neurons that leads to motor symptoms. The etiology and pathogenesis of PD are not clear. We found that expression of COUP-TFII, an orphan nuclear receptor, in DA neurons is upregulated i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Genet
मुख्य लेखकों: Kao, Chung-Yang, Xu, Mafei, Wang, Leiming, Lin, Shih-Chieh, Lee, Hui-Ju, Duraine, Lita, Bellen, Hugo J., Goldstein, David S., Tsai, Sophia Y., Tsai, Ming-Jer
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2020
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340320/
https://ncbi.nlm.nih.gov/pubmed/32579581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008868
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन