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Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes

Invader probes, i.e., DNA duplexes modified with +1 interstrand zippers of intercalator-functionalized nucleotides like 2’-O-(pyren-1-yl)methyl-RNA monomers, are energetically activated for sequence-unrestricted recognition of double-stranded DNA (dsDNA) as they are engineered to violate the neighbo...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Guenther, Dale C., Emehiser, Raymond G., Inskeep, Allison, Karmakar, Saswata, Hrdlicka, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340116/
https://ncbi.nlm.nih.gov/pubmed/32520054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ob01052a
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