Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness

BACKGROUND: High-grade gliomas likely remodel the metabolic machinery to meet the increased demands for amino acids and nucleotides during rapid cell proliferation. Glycine, a non-essential amino acid and intermediate of nucleotide biosynthesis, may increase with proliferation. Non-invasive measurem...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Tiwari, Vivek, Daoud, Elena V, Hatanpaa, Kimmo J, Gao, Ang, Zhang, Song, An, Zhongxu, Ganji, Sandeep K, Raisanen, Jack M, Lewis, Cheryl M, Askari, Pegah, Baxter, Jeannie, Levy, Michael, Dimitrov, Ivan, Thomas, Binu P, Pinho, Marco C, Madden, Christopher J, Pan, Edward, Patel, Toral R, DeBerardinis, Ralph J, Sherry, A Dean, Mickey, Bruce E, Malloy, Craig R, Maher, Elizabeth A, Choi, Changho
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Neuroimaging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339885/
https://ncbi.nlm.nih.gov/pubmed/32055850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa034
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