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Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications

Proper brain function relies on the precise arrangement and flow of information between diverse neural subtypes. Developing improved human cell-based models which faithfully mimic biologically relevant connectivity patterns may improve drug screening efforts given the limited success of animal model...

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Bibliographic Details
Published in:Lab Chip
Main Authors: Fantuzzo, Joseph A., Robles, Denise A., Mirabella, Vincent R., Hart, Ronald P., Pang, Zhiping P., Zahn, Jeffrey D.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339603/
https://ncbi.nlm.nih.gov/pubmed/32064487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9lc01179j
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