Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis. Screening for remyelination is problematic, as myelination requires the presence of axons. Standard methods do not resolve cell-autonomous effec...

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Veröffentlicht in:Nat Med
Hauptverfasser: Mei, Feng, Fancy, Stephen P J, Shen, Yun-An A, Niu, Jianqin, Zhao, Chao, Presley, Bryan, Miao, Edna, Lee, Seonok, Mayoral, Sonia R, Redmond, Stephanie A, Etxeberria, Ainhoa, Xiao, Lan, Franklin, Robin J M, Green, Ari, Hauser, Stephen L, Chan, Jonah R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830134/
https://ncbi.nlm.nih.gov/pubmed/24997607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3618
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