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TNF-α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR-335-5p

Elucidation of the underlying mechanisms governing osteogenic differentiation is of significant importance to the improvement of therapeutics for bone-related inflammatory diseases. Tumor necrosis factor-α (TNF-α) is regarded as one of the major agents during osteogenic differentiation in an inflamm...

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Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: Li, Shanshan, Yin, Yixin, Yao, Liping, Lin, Ziyi, Sun, Shengjun, Zhang, Jin, Li, Xiaoyan
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339467/
https://ncbi.nlm.nih.gov/pubmed/32468044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11152
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