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Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

Microtubule‐depolymerizing agents can selectively disrupt tumor vessels via inducing endothelial membrane blebbing. However, the mechanism regulating blebbing is largely unknown. IMB5046 is a newly discovered microtubule‐depolymerizing agent. Here, the functions of focal adhesion kinase (FAK) during...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Zheng, Yan‐Bo, Gong, Jian‐Hua, Zhen, Yong‐Su
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339229/
https://ncbi.nlm.nih.gov/pubmed/32452639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15273
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