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Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

Microtubule‐depolymerizing agents can selectively disrupt tumor vessels via inducing endothelial membrane blebbing. However, the mechanism regulating blebbing is largely unknown. IMB5046 is a newly discovered microtubule‐depolymerizing agent. Here, the functions of focal adhesion kinase (FAK) during...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Zheng, Yan‐Bo, Gong, Jian‐Hua, Zhen, Yong‐Su
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339229/
https://ncbi.nlm.nih.gov/pubmed/32452639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15273
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