Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3

BACKGROUND: Bone marrow stem cell clonal dysfunction by somatic mutation is suspected to affect post-infarction myocardial regeneration after coronary bypass surgery (CABG). METHODS: Transcriptome and variant expression analysis was studied in the phase 3 PERFECT trial post myocardial infarction CAB...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wolfien, Markus, Klatt, Denise, Salybekov, Amankeldi A., Ii, Masaaki, Komatsu-Horii, Miki, Gaebel, Ralf, Philippou-Massier, Julia, Schrinner, Eric, Akimaru, Hiroshi, Akimaru, Erika, David, Robert, Garbade, Jens, Gummert, Jan, Haverich, Axel, Hennig, Holger, Iwasaki, Hiroto, Kaminski, Alexander, Kawamoto, Atsuhiko, Klopsch, Christian, Kowallick, Johannes T., Krebs, Stefan, Nesteruk, Julia, Reichenspurner, Hermann, Ritter, Christian, Stamm, Christof, Tani-Yokoyama, Ayumi, Blum, Helmut, Wolkenhauer, Olaf, Schambach, Axel, Asahara, Takayuki, Steinhoff, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339012/
https://ncbi.nlm.nih.gov/pubmed/32629392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102862
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