A carregar...
AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing
Oncogenic mouse double minute 2 homolog (MDM2) is an E3-ubiquitin ligase that facilitates proteasomal degradation of p53. MDM2 amplification occurs in cancer and has been implicated in accelerated tumor growth, known as hyper-progression, following immune-checkpoint therapy. MDM2 amplification also...
Na minha lista:
| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7338458/ https://ncbi.nlm.nih.gov/pubmed/32655895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0292-1 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|