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Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells
Testing new ways to identify untapped opportunities for glioblastoma therapies remains highly significant. Amplification and overexpression of MDM2 gene is frequent in glioblastoma and disrupting the MDM2−p53 interaction is a promising strategy to treat the cancer. RG7112 is the first-in class inhib...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052082/ https://ncbi.nlm.nih.gov/pubmed/30022047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0825-1 |
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