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Targeting focal adhesion kinase in cancer cells and the tumor microenvironment

Focal adhesion kinase (FAK) is an integrin-associated protein tyrosine kinase that is frequently overexpressed in advanced human cancers. Recent studies have demonstrated that aside from FAK’s catalytic activity in cancer cells, its cellular localization is also critical for regulating the transcrip...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Murphy, James M., Rodriguez, Yelitza A. R., Jeong, Kyuho, Ahn, Eun-Young Erin, Lim, Ssang-Taek Steve
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338452/
https://ncbi.nlm.nih.gov/pubmed/32514188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0447-4
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