Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-mediated Cyclin D1 Transcription

RATIONALE: Neointimal hyperplasia is characterized by excessive accumulation of vascular smooth muscle cells (SMCs) leading to occlusive disorders such as atherosclerosis and stenosis. Blood vessel injury increases growth factor secretion and matrix synthesis, which promotes SMC proliferation and ne...

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Publicado no:Circ Res
Main Authors: Jeong, Kyuho, Kim, Jung-Hyun, Murphy, James M., Park, Hyeonsoo, Kim, Su-Jeong, Rodriguez, Yelitza A.R., Kong, Hyunkyung, Choi, Chungsik, Guan, Jun-Lin, Taylor, Joan M., Lincoln, Thomas M., Gerthoffer, William T., Kim, Jun-Sub, Ahn, Eun-Young Erin, Schlaepfer, David D., Lim, Ssang-Taek Steve
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702425/
https://ncbi.nlm.nih.gov/pubmed/31096851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.314344
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