Requirements for the differentiation of innate T-bet(high) memory-phenotype CD4(+) T lymphocytes under steady state

CD4(+) T lymphocytes consist of naïve, antigen-specific memory, and memory-phenotype (MP) cell compartments at homeostasis. We recently showed that MP cells exert innate-like effector function during host defense, but whether MP CD4(+) T cells are functionally heterogeneous and, if so, what signals...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Kawabe, Takeshi, Yi, Jaeu, Kawajiri, Akihisa, Hilligan, Kerry, Fang, Difeng, Ishii, Naoto, Yamane, Hidehiro, Zhu, Jinfang, Jankovic, Dragana, Kim, Kwang Soon, Trinchieri, Giorgio, Sher, Alan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338451/
https://ncbi.nlm.nih.gov/pubmed/32632165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17136-1
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