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Memory-phenotype CD4(+) T cells spontaneously generated under steady state conditions exert innate Th1-like effector function

Conventional CD4(+) T cells are composed of naïve, pathogen-specific memory, and pathogen-independent memory-phenotype (MP) cells under steady state. Naïve and pathogen-specific memory cells play key roles in adaptive immunity, whereas the homeostatic mechanisms regulating the generation of MP cells...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Kawabe, Takeshi, Jankovic, Dragana, Kawabe, Shuko, Huang, Yuefeng, Lee, Ping-Hsien, Yamane, Hidehiro, Zhu, Jinfang, Sher, Alan, Germain, Ronald N., Paul, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568832/
https://ncbi.nlm.nih.gov/pubmed/28783663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aam9304
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