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Acquiring and Analyzing Data Independent Acquisition Proteomics Experiments without Spectrum Libraries

Data independent acquisition (DIA) is an attractive alternative to standard shotgun proteomics methods for quantitative experiments. However, most DIA methods require collecting exhaustive, sample-specific spectrum libraries with data dependent acquisition (DDA) to detect and quantify peptides. In a...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Pino, Lindsay K., Just, Seth C., MacCoss, Michael J., Searle, Brian C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338082/
https://ncbi.nlm.nih.gov/pubmed/32312845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.P119.001913
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