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Using neighboring-group participation for acyclic stereocontrol in diastereoselective substitution reactions of acetals

Neighboring-group participation of an ester enabled stereocontrol in substitution reactions of acyclic acetals. The ester group formed a trans-fused dioxolenium ion intermediate, which underwent a substitution reaction at the acetal carbon atom to afford the product with high diastereoselectivity. N...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Ramdular, Amanda, Woerpel, K. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337985/
https://ncbi.nlm.nih.gov/pubmed/32392075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01166
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