Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma

Individual colorectal adenomas have different propensities to progress to invasive disease. In this study, we explored whether these differences could be explained by gene copy number alterations. We evaluated 18 adenomas of patients without synchronous or subsequent carcinoma (6.5 years follow-up),...

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Publicat a:Mod Pathol
Autors principals: Habermann, Jens K, Brucker, Constanze A, Freitag-Wolf, Sandra, Heselmeyer-Haddad, Kerstin, Krüger, Stefan, Barenboim, Linda, Downing, Tricia, Bruch, Hans-Peter, Auer, Gert, Roblick, Uwe J, Ried, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337970/
https://ncbi.nlm.nih.gov/pubmed/21102417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.217
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