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Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma

Individual colorectal adenomas have different propensities to progress to invasive disease. In this study, we explored whether these differences could be explained by gene copy number alterations. We evaluated 18 adenomas of patients without synchronous or subsequent carcinoma (6.5 years follow-up),...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Habermann, Jens K, Brucker, Constanze A, Freitag-Wolf, Sandra, Heselmeyer-Haddad, Kerstin, Krüger, Stefan, Barenboim, Linda, Downing, Tricia, Bruch, Hans-Peter, Auer, Gert, Roblick, Uwe J, Ried, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337970/
https://ncbi.nlm.nih.gov/pubmed/21102417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.217
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