Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma

Individual colorectal adenomas have different propensities to progress to invasive disease. In this study, we explored whether these differences could be explained by gene copy number alterations. We evaluated 18 adenomas of patients without synchronous or subsequent carcinoma (6.5 years follow-up),...

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Pubblicato in:Mod Pathol
Autori principali: Habermann, Jens K, Brucker, Constanze A, Freitag-Wolf, Sandra, Heselmeyer-Haddad, Kerstin, Krüger, Stefan, Barenboim, Linda, Downing, Tricia, Bruch, Hans-Peter, Auer, Gert, Roblick, Uwe J, Ried, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337970/
https://ncbi.nlm.nih.gov/pubmed/21102417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.217
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