Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

Monocytes and macrophages are essential components of the innate immune system. Herein, we report that intron retention (IR) plays an important role in the development and function of these cells. Using Illumina mRNA sequencing, Nanopore direct cDNA sequencing and proteomics analysis, we identify IR...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Green, Immanuel D, Pinello, Natalia, Song, Renhua, Lee, Quintin, Halstead, James M, Kwok, Chau-To, Wong, Alex C H, Nair, Shalima S, Clark, Susan J, Roediger, Ben, Schmitz, Ulf, Larance, Mark, Hayashi, Rippei, Rasko, John E J, Wong, Justin J-L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Data Resources and Analyses
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337907/
https://ncbi.nlm.nih.gov/pubmed/32449925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa435
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