Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation

Clinical manifestations of coronavirus disease 2019 (COVID-19) vary from asymptomatic virus shedding, nonspecific pharyngitis, to pneumonia with silent hypoxia and respiratory failure. Dendritic cells and macrophages are sentinel cells for innate and adaptive immunity that affect the pathogenesis of...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Yang, Dong, Chu, Hin, Hou, Yuxin, Chai, Yue, Shuai, Huiping, Lee, Andrew Chak-Yiu, Zhang, Xi, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337793/
https://ncbi.nlm.nih.gov/pubmed/32563187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa356
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