Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation

Clinical manifestations of coronavirus disease 2019 (COVID-19) vary from asymptomatic virus shedding, nonspecific pharyngitis, to pneumonia with silent hypoxia and respiratory failure. Dendritic cells and macrophages are sentinel cells for innate and adaptive immunity that affect the pathogenesis of...

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發表在:J Infect Dis
Main Authors: Yang, Dong, Chu, Hin, Hou, Yuxin, Chai, Yue, Shuai, Huiping, Lee, Andrew Chak-Yiu, Zhang, Xi, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Major Articles and Brief Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337793/
https://ncbi.nlm.nih.gov/pubmed/32563187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa356
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