Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation

Clinical manifestations of coronavirus disease 2019 (COVID-19) vary from asymptomatic virus shedding, nonspecific pharyngitis, to pneumonia with silent hypoxia and respiratory failure. Dendritic cells and macrophages are sentinel cells for innate and adaptive immunity that affect the pathogenesis of...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Yang, Dong, Chu, Hin, Hou, Yuxin, Chai, Yue, Shuai, Huiping, Lee, Andrew Chak-Yiu, Zhang, Xi, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337793/
https://ncbi.nlm.nih.gov/pubmed/32563187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa356
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