Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging coronavirus that has resulted in nearly 1,000,000 laboratory-confirmed cases including over 50,000 deaths. Although SARS-CoV-2 and SARS-CoV share a number of common clinical manifestations, SARS-CoV-2 appears to...

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Gepubliceerd in:Clin Infect Dis
Hoofdauteurs: Chu, Hin, Chan, Jasper Fuk-Woo, Wang, Yixin, Yuen, Terrence Tsz-Tai, Chai, Yue, Hou, Yuxin, Shuai, Huiping, Yang, Dong, Hu, Binjie, Huang, Xiner, Zhang, Xi, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Kok, Kin-Hang, To, Kelvin Kai-Wang, Chan, Ivy Hau-Yee, Zhang, Anna Jinxia, Sit, Ko-Yung, Au, Wing-Kuk, Yuen, Kwok-Yung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Major Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184390/
https://ncbi.nlm.nih.gov/pubmed/32270184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciaa410
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