Translation at first sight: the influence of leading codons

First triplets of mRNA coding region affect the yield of translation. We have applied the flowseq method to analyze >30 000 variants of the codons 2–11 of the fluorescent protein reporter to identify factors affecting the protein synthesis. While the negative influence of mRNA secondary structure...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Osterman, Ilya A, Chervontseva, Zoe S, Evfratov, Sergey A, Sorokina, Alena V, Rodin, Vladimir A, Rubtsova, Maria P, Komarova, Ekaterina S, Zatsepin, Timofei S, Kabilov, Marsel R, Bogdanov, Alexey A, Gelfand, Mikhail S, Dontsova, Olga A, Sergiev, Petr V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337518/
https://ncbi.nlm.nih.gov/pubmed/32427319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa430
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