Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission

The COVID-19 pandemic has sparked an urgent need to uncover the underlying biology of this devastating disease. Though RNA viruses mutate more rapidly than DNA viruses, there are a relatively small number of single nucleotide polymorphisms (SNPs) that differentiate the main SARS-CoV-2 clades that ha...

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Publicat a:bioRxiv
Autors principals: Sapoval, Nicolae, Mahmoud, Medhat, Jochum, Michael D., Liu, Yunxi, Elworth, R. A. Leo, Wang, Qi, Albin, Dreycey, Ogilvie, Huw, Lee, Michael D., Villapol, Sonia, Hernandez, Kyle M., Berry, Irina Maljkovic, Foox, Jonathan, Beheshti, Afshin, Ternus, Krista, Aagaard, Kjersti M., Posada, David, Mason, Christopher E., Sedlazeck, Fritz, Treangen, Todd J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337385/
https://ncbi.nlm.nih.gov/pubmed/32637955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.02.184481
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