Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission

The COVID-19 pandemic has sparked an urgent need to uncover the underlying biology of this devastating disease. Though RNA viruses mutate more rapidly than DNA viruses, there are a relatively small number of single nucleotide polymorphisms (SNPs) that differentiate the main SARS-CoV-2 clades that ha...

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Vydáno v:bioRxiv
Hlavní autoři: Sapoval, Nicolae, Mahmoud, Medhat, Jochum, Michael D., Liu, Yunxi, Elworth, R. A. Leo, Wang, Qi, Albin, Dreycey, Ogilvie, Huw, Lee, Michael D., Villapol, Sonia, Hernandez, Kyle M., Berry, Irina Maljkovic, Foox, Jonathan, Beheshti, Afshin, Ternus, Krista, Aagaard, Kjersti M., Posada, David, Mason, Christopher E., Sedlazeck, Fritz, Treangen, Todd J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337385/
https://ncbi.nlm.nih.gov/pubmed/32637955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.02.184481
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