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PD-L1 upregulation by IFN-α/γ-mediated Stat1 suppresses anti-HBV T cell response
Programmed death ligand 1 (PD-L1) has been recently shown to be a major obstacle to antiviral immunity by binding to its receptor programmed death 1 (PD-1) on specific IFN-γ producing T cells in chronic hepatitis B. Currently, IFN-α is widely used to treat hepatitis B virus (HBV) infection, but its...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337294/ https://ncbi.nlm.nih.gov/pubmed/32628668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228302 |
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