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Structural analysis of missense mutations occurring in the DNA-binding domain of HSF4 associated with congenital cataracts
Congenital cataract (CC) is the major cause of childish blindness, and nearly 50% of CCs are hereditary disorders. HSF4, a member of the heat shock transcription factor family, acts as a key regulator of cell growth and differentiation during the development of sensory organs. Missense mutations in...
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| Publicado no: | J Struct Biol X |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337047/ https://ncbi.nlm.nih.gov/pubmed/32647819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjsbx.2019.100015 |
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