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Tartryl-CoA inhibits succinyl-CoA synthetase

Succinyl-CoA synthetase (SCS) catalyzes the only substrate-level phosphoryl­ation step in the tricarboxylic acid cycle. Human GTP-specific SCS (GTPSCS), an αβ-heterodimer, was produced in Escherichia coli. The purified protein crystallized from a solution containing tartrate, CoA and magnesium chlor...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr F Struct Biol Commun
Main Authors: Huang, Ji, Fraser, Marie E.
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336359/
https://ncbi.nlm.nih.gov/pubmed/32627745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20008201
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