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Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization

Proline/alanine-rich sequence (PAS) polypeptides represent a novel class of biosynthetic polymers comprising repetitive sequences of the small proteinogenic amino acids l-proline, l-alanine and/or l-serine. PAS polymers are strongly hydrophilic and highly soluble in water, where they exhibit a nativ...

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Foilsithe in:Acta Crystallogr F Struct Biol Commun
Main Authors: Schiefner, André, Walser, Rebecca, Gebauer, Michaela, Skerra, Arne
Formáid: Artigo
Teanga:Inglês
Foilsithe: International Union of Crystallography 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336357/
https://ncbi.nlm.nih.gov/pubmed/32627748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20008328
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