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Modulation of Self-Association and Subsequent Fibril Formation in an Alanine-Rich Helical Polypeptide

Thermal unfolding, reversible self-association, and irreversible aggregation were investigated for an alanine-rich helical polypeptide, 17-H-6, with sequence [AAAQEAAAAQAAAQAEAAQAAQ](6). Dynamic light scattering, transmission electron microscopy, and thermal unfolding measurements indicate that 17-H...

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Detalhes bibliográficos
Main Authors: Top, Ayben, Kiick, Kristi L., Roberts, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606058/
https://ncbi.nlm.nih.gov/pubmed/18452331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm800056r
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