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The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors

Translocase of outer mitochondrial membrane 34 (TOMM34) orchestrates heat shock protein 70 (HSP70)/HSP90–mediated transport of mitochondrial precursor proteins. Here, using in vitro phosphorylation and refolding assays, analytical size-exclusion chromatography, and hydrogen/deuterium exchange MS, we...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Trcka, Filip, Durech, Michal, Vankova, Pavla, Vandova, Veronika, Simoncik, Oliver, Kavan, Daniel, Vojtesek, Borivoj, Muller, Petr, Man, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335785/
https://ncbi.nlm.nih.gov/pubmed/32371396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012624
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