Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding

Eukaryotic protein homeostasis (proteostasis) is largely dependent on the action of highly conserved Hsp70 molecular chaperones. Recent evidence indicates that, apart from conserved molecular allostery, Hsp70 proteins have retained and adapted the ability to assemble as functionally relevant ATP-bou...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Trcka, Filip, Durech, Michal, Vankova, Pavla, Chmelik, Josef, Martinkova, Veronika, Hausner, Jiri, Kadek, Alan, Marcoux, Julien, Klumpler, Tomas, Vojtesek, Borivoj, Muller, Petr, Man, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356074/
https://ncbi.nlm.nih.gov/pubmed/30459217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.001044
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