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Mycobacterium tuberculosis (Mtb) lipid mediated lysosomal rewiring in infected macrophages modulates intracellular Mtb trafficking and survival

Intracellular pathogens commonly manipulate the host lysosomal system for their survival. However, whether this pathogen-induced alteration affects the organization and functioning of the lysosomal system itself is not known. Here, using in vitro and in vivo infections and quantitative image analysi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sachdeva, Kuldeep, Goel, Manisha, Sudhakar, Malvika, Mehta, Mansi, Raju, Rajmani, Raman, Karthik, Singh, Amit, Sundaramurthy, Varadharajan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335774/
https://ncbi.nlm.nih.gov/pubmed/32424041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012809
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