Mycobacterium tuberculosis (Mtb) lipid mediated lysosomal rewiring in infected macrophages modulates intracellular Mtb trafficking and survival

Intracellular pathogens commonly manipulate the host lysosomal system for their survival. However, whether this pathogen-induced alteration affects the organization and functioning of the lysosomal system itself is not known. Here, using in vitro and in vivo infections and quantitative image analysi...

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Vydáno v:J Biol Chem
Hlavní autoři: Sachdeva, Kuldeep, Goel, Manisha, Sudhakar, Malvika, Mehta, Mansi, Raju, Rajmani, Raman, Karthik, Singh, Amit, Sundaramurthy, Varadharajan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335774/
https://ncbi.nlm.nih.gov/pubmed/32424041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012809
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