A New Pharmacokinetic Model Describing the Biodistribution of Intravenously and Intratumorally Administered Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in a GL261 Xenograft Glioblastoma Model

BACKGROUND: Superparamagnetic iron oxide nanoparticles (SPIONs) have displayed multifunctional applications in cancer theranostics following systemic delivery. In an effort to increase the therapeutic potential of local therapies (including focal hyperthermia), nanoparticles can also be administered...

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Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Klapproth, Alexander P, Shevtsov, Maxim, Stangl, Stefan, Li, Wei Bo, Multhoff, Gabriele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335747/
https://ncbi.nlm.nih.gov/pubmed/32669844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S254745
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